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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754dde71d7061a0382276aa187d085f7c264758a4e67e005e81983c88ff52e3f' 
  AND token = 'tia0KL2pCIO/Xm6AY22BiThYF0SzkZ3EXZFaVyAEU3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}