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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2078153054ffc3a69979e067bd75a3a0f2e7f3e716eeb6b0e7acb350037139fd' 
  AND token = '8ufcD+9lvpESSo4WXgVEM2u8hZaTXOFtDEo4gaQdujk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}