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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2d65953b853c2193bc7f57f814bab3b18d77a8d77a36ec58c938c57a87d862' 
  AND token = 'YCeOytwdpXU1T8g/CJQ0WoeitJDMUaf7zQjLYCyEEKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}