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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd69218fc15c54efa7fd6c69cd2f29c36a1342cfe4fa77c08da7d171bee3fc429' 
  AND token = 'p2ifvuJN8SIM3oy9eeYN+09rSsQRqQVgA0KVjliUOtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}