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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bcb99a2ba68dd473e952b4a995494563c8f44c1dc273c8c90f5c65be363228d' 
  AND token = 'JbjM9oEE9EwG0fP/k9aZWo0sC3pEw3TOT27iwaw0Tbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}