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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efd7d24f42c18f8a2d9999b399ed44a937db48f6a1b3c90bedcf13ac448ccdf' 
  AND token = '1kOFKp6WtTFyZ+uby2rYKKCDh3rZJbiVBtQCXZkhC74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}