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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50cb9e0a88a88c486b2fba4f5e9624079aacf27b63231000dfb8286df43adb81' 
  AND token = 'OsP2TqLv2yyD7MwOMl5985EU6aGy5T9ARN5FYTohoKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}