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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '632a6560e326ed9368c96bd742b3f227601153188cade722494e17f936e40b78' 
  AND token = 'u1/cd5Afcfyp9GVQZcEzYM0FpkLMsmuLY81YAIs1SlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}