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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4212dace406b96f7e3cacd8f0a305268d3cc90cab819066faa3a21318d0792' 
  AND token = 'Rm+OooWzecW97OE07RhWMHk+c6VtaZWBibj1x/1KBo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}