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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3cc90b59128bfcbcf85020f1c21f38c71eeee27d61253c7a9f1b90629f01f2' 
  AND token = '2N5VlXmQD7GdyDrsvXXN294YQIkPvJpbNQ9Crno5nuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}