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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab50c7efc23e8f3a744384d46a99257bc8fa145df47012c78bab6c2112b30d6e' 
  AND token = 'IHSNOdTigAxw7ztFKprn/k+cBnkT4H5fhR+Fmuu9SII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}