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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b809e0bde5400944369d410857c83f9e99ed96fdcd552eb4979308e65d6d36f1' 
  AND token = 't5I5SyoFxsLynPhmtUaUQ95WMzVpGY4dDPdANxzRNVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}