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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14007570e5b4008521de302a92fc89b6fe4939d17340f676f14dbdad343f011' 
  AND token = 'UmWhLjTQ0Mh+9GLQRfVfZUxxtl5XaTG41D0DjXuq1M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}