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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e26e73295568fbf1f5e9dac3585771179519374d4be0a80495b23e86a8e0019' 
  AND token = 'yDE7UAb91K6Gb+keu86ioYk9Iv+K28V/SHrxOvVJZD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}