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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5cfb85bad2e6b3ecbd1b12172b5c44a80f8ad15a6820ac3af5e70af4a89a2a4' 
  AND token = '4ayK7D4kP29iW//DWR73E46JQIyDjLgp/yRs4+EYrAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}