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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c58493fa232e993b0658c3cfc2dfbe2cde2f5037fe309a906c97a93df7a522e' 
  AND token = 'OebIyxnpLSey+RZ2Jq7z+C6MNiuwnp5glKv0BUAIxu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}