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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31215f2c7c00c4b1340d132dd9310638c8f04b8a16d4375853b210cabf623cce' 
  AND token = '3RnDQK/IPLGNsnByKOzB5A+xWvUdH2+b1/n05iNnMsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}