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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54407cc1ad71082e4349e81844f6cb34615384467d0d8f0d3ea4280d2af56f1f' 
  AND token = '9DfPvVxwWXuqp9FUCzVGyPGy0Kf4z/hi53VA6S8+8NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}