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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb50a71d3c7dbf0cbf343346680baee64a3bd9e030622904046a4acbbbd30e0' 
  AND token = 'W2pLvGro2mte/PjTwhXdy5C+Pm2YKwUVVLR2pOTzelA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}