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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c0f12a8b9df42e4bc20f7641ce86f10068b38752063a3b0b937f38756e582b' 
  AND token = 'S/Ufb4Q+FmMJ+5JxSANpXbVafrUEC8LIIJO37pt2KmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}