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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0cf4fc5487cdf7879498d477b02b017182a1ea9499da95b01a647d565919bd' 
  AND token = 'p+QAtpehmikJxz1SXqiiuVh5qESaHvjcehsMJ4W+oAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}