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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc7a29cc19aff259ce896938db125c988c28164d07a3bd01f8eac89039f0e5c4' 
  AND token = 'MJKav87e9WK9b6b7nWfb1w03U8NtFMcwSPSZgAB8Dtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}