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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38185c1c87915059d1b5e4fd215cf9d730dd44558a3517e1a0f61bf26860b58f' 
  AND token = '0T2G6k4x/WZuU1sJBOTIPDqQ3GzmCWq1D1dU1SBIYZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}