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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d0720ba79b803e51b2d2850fb9dc399d63e9f093e651e472dea289d8c5d27c' 
  AND token = 'KeA+255DAkwRwzRG6Gr4t5783d37CCnA6lzSQ3VX4NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}