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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3ff5a80e9a39ac0e07358491b8203406432ad0d86f989a421106b4dcac48f28' 
  AND token = 'lkGZ38aEu4RoIPgtSYrUS9RndvJbeppHT+dvDO66zJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}