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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d72c1640c9b676ad934a99dc80a38dde479f3b7f16d0ab74a2cf9540e83408' 
  AND token = 'G77LYrTVEXqIsVOD6eoA51+FFkLFX+0rq5u225/PTOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}