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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b8cf722a69006e7f4c217ca5ffbbad42945069a667bf9deda4cca33de7cdcb' 
  AND token = 'hAUCJ1Kz3RiGOMCiU3HrqH2cTSYIwrEMfvM9TsXVS0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}