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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec8ab69c6a5582970396a4421a14f1fec218cfe2f2838b90c4ce8bbc8665a16' 
  AND token = 'cGGQpgpLwbduCX8CwiZDWdK7zMz9GElLhtb0nXbJxFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}