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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66708f69b5ca528285eb302f26eabd0c365f2e51b6a7dcc69af1073b822e3a5' 
  AND token = 'j6tTRxIo0DgG+h0K9T63RM3PZtExGz9/z6FwHsmKue0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}