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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb0e3155e42de7708dce28221f0e62de349f651cf798e41309c8b1e9b5a7688' 
  AND token = 'lyUgdUQJzRJCpQXsU7W/bDaFY/gcsXCWQGmrni6t9XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}