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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22a292cf06c40a7664edb02621a40871b101c5975a9ce15022097eda1ec7637' 
  AND token = 'Au2VqCDe0ockMTFJWuDWOSDao5qe2zEQ9UodW2V5yB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}