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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50ffcf730acaff624ef226e153af0b42e18a9af08f16c7cc2e1dd7ac6722e45' 
  AND token = 'kVbfKlAzoqEWDiu5Ymf1LQ2DvTOk/zJVjO6c5J0yU04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}