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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af54606e0d9e3995a5e42f3f3c8c9907def0ed1c1ae3faa2ce036fc559067103' 
  AND token = '6K4U6tl8stCxD3d6jaXVZcy/y+2HALVdxQNAfLEx0Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}