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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c57e17479979f373e3deb01f1a553e48314ba7bd8efb1757f6332f74b2a577' 
  AND token = 'mflwmm9FxK8Ko5p/cMsI34/XF59HEWxNy/lgjDfwPe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}