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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f50ceac3863672d932eeb20e34e8af68950208841686142b113be1cd434197' 
  AND token = 'bZeEBEzzRc9m+p6vvWUs6wuHGjLoNAg/BbprceqF3n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}