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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4a2231f0d9b193cc3d0a0bb2022a89c4e20729914a178c4a86fead6d96d7e0' 
  AND token = 'rPEZRGGqxaMCr87IQ0YujknmQTYI+33t9AOJ0dQtDnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}