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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf6a65fb16fecd0be6a852d7b18514bddc74c95f05242203f2189fef1cce46f1' 
  AND token = '/P4/Oaz8/fZs7RyAbJFq/JnADxBq3twe9On9qBheLsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}