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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a4c02e111236e2b70e2c9eca51650303707669d4de59abdb23294973e560cd' 
  AND token = 'grG+JuFizKoJsVz9fkzJ6NnoXAeUpjV4+SeuIL5s7Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}