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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7577eaaa25bff298b14832ab711d71bc46cd11bea1236cce7638d869c024a25' 
  AND token = '0mw25kZdkYRQeJjvPVvP+Dy9JrjZOt7TT4Fa53p1mqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}