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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546d006f4c7335da0ab672870dfd4aaa35e26ae59c49cbe0bb4420bea3587a47' 
  AND token = 'a6gGgA+fVk6C/+Wz/qTHIDZpi3WNIm5vSzOKCFytHWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}