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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54116423b28e7a5dfe6b80454ef3b00d296f162728f26bbb2b2ec75356c6dab' 
  AND token = 'xtI0SPMnQzI/9JMRch1cBvKbnm0GeQti8O/9vCB5wKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}