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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acfafdda2c063d189d74a363e27ae347f827ef187f98602e24620b5f71609d81' 
  AND token = 'EvxY+ACYY5M1Zva5i/9WFjC6TdVLWjcUMNnjQ+nSJ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}