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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbb383c2b42f362a2cda52fa3d7b095b755848c0ff2c3059c3cb599a30edb5f5' 
  AND token = 'LQFk3ZlEefIx9uNrMKU8KsU+iuFwErasY8qmyxKmJcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}