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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dd4cb18dfab4e0f314423dde4e011f4bc957a0a040d8657ffa3e9bcd9dc386a' 
  AND token = 'sEDGUj9cSoh0PUy0cKvvRSTA5ZsBNP3A2fDQktQWPUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}