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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4240a501bc562c6a678b5cde6d3981f51b8a54f6cd948865950933010543b96d' 
  AND token = 'JZRVi2IYIdeDP2f8UjP+cUZKF+VyBVYtpfJ5CbWQ9x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}