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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea7dab4fd78271eb5acde2b7b6941c4224a9d2df3874327c5ee4392637922e1d' 
  AND token = 't7LVg+/eQi3xwdMP88ifAFHPcsDkdiLCxbdHQqjhX7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}