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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca4c377de7b6f5f61aa8e3c33dec879dc21b1abfda2431cc10c680487d7daaf' 
  AND token = 'z9LtoFjuOaJ+4qLehRT129uACucf1A2ZFPjNJ5FP6J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}