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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec653e5a7769b565bf7f9cb821be09574c24bc75680a788ff89ac3c9a22c437' 
  AND token = 'CxVXdXfY9hVe3z/nrJZHc2i2HqqijWTfwjlyncvD2eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}