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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b862694e301ebca8e857ce2daec8d4bc9d8aa84c0e62efc5033201e7d2b3489' 
  AND token = 'nYO97Lqr06E+AlGY8H7n+ktCwkKf7cD3VcEKQFoqQmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}