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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332736123f73c2fcf0b818ab88ae2594e36080580e67ad545c755244bc164d6f' 
  AND token = 'JN9RtL8N21yv42KYDdHos+RXILmfgdUbV9HEf2sKFKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}